Ro 60-0175

CAS No. 169675-08-5

Ro 60-0175 ( Ro 600175 )

Catalog No. M12587 CAS No. 169675-08-5

Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 237 Get Quote
10MG 380 Get Quote
25MG 620 Get Quote
50MG 883 Get Quote
100MG 1215 Get Quote
500MG 2412 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Ro 60-0175
  • Note
    Research use only, not for human use.
  • Brief Description
    Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.
  • Description
    Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively; induces hypolocomotion in rats at doses greater than 0.5 mg/kg s.c.; (0.3 and 1 mg/kg s.c.) simultaneously reduces both unpunished and punished lever pressing, a profile consistent with sedation, induces sedative-like responses via 5-HT(2C) receptor activation in vivo.
  • Synonyms
    Ro 600175
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    169675-08-5
  • Formula Weight
    226.68
  • Molecular Formula
    C11H12ClFN2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(CN1C=CC2=CC(=C(C=C21)Cl)F)N.C(=CC(=O)O)C(=O)O
  • Chemical Name
    1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (S)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Damjanoska KJ, et al. J Pharmacol Exp Ther. 2003 Mar;304(3):1209-16.
2. Vickers SP, et al. Br J Pharmacol. 2000 Jul;130(6):1305-14.
3. Kennett G, et al. Eur J Pharmacol. 2000 Jan 10;387(2):197-204.
4. Jenck F, et al. Eur Neuropsychopharmacol. 1998 Aug;8(3):161-8.
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