Ro 60-0175
CAS No. 169675-08-5
Ro 60-0175 ( Ro 600175 )
Catalog No. M12587 CAS No. 169675-08-5
Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 237 | Get Quote |
|
10MG | 380 | Get Quote |
|
25MG | 620 | Get Quote |
|
50MG | 883 | Get Quote |
|
100MG | 1215 | Get Quote |
|
500MG | 2412 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRo 60-0175
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NoteResearch use only, not for human use.
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Brief DescriptionRo 60-0175 is a potent, selective 5-HT2C receptor agonist.
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DescriptionRo 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively; induces hypolocomotion in rats at doses greater than 0.5 mg/kg s.c.; (0.3 and 1 mg/kg s.c.) simultaneously reduces both unpunished and punished lever pressing, a profile consistent with sedation, induces sedative-like responses via 5-HT(2C) receptor activation in vivo.
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SynonymsRo 600175
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number169675-08-5
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Formula Weight226.68
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Molecular FormulaC11H12ClFN2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(CN1C=CC2=CC(=C(C=C21)Cl)F)N.C(=CC(=O)O)C(=O)O
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Chemical Name1H-Indole-1-ethanamine, 6-chloro-5-fluoro-α-methyl-, (S)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Damjanoska KJ, et al. J Pharmacol Exp Ther. 2003 Mar;304(3):1209-16.
2. Vickers SP, et al. Br J Pharmacol. 2000 Jul;130(6):1305-14.
3. Kennett G, et al. Eur J Pharmacol. 2000 Jan 10;387(2):197-204.
4. Jenck F, et al. Eur Neuropsychopharmacol. 1998 Aug;8(3):161-8.
2. Vickers SP, et al. Br J Pharmacol. 2000 Jul;130(6):1305-14.
3. Kennett G, et al. Eur J Pharmacol. 2000 Jan 10;387(2):197-204.
4. Jenck F, et al. Eur Neuropsychopharmacol. 1998 Aug;8(3):161-8.
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